This is the leading international professional reference text that also serves as a bench book, describing all aspects of the pathology of brain tumours - genetics, molecular biology, epidemiology, morphology, immunohistochemistry, diagnostic criteria and prognosis. Beautifully illustrated in colour throughout and comprehensively referenced, Russell & Rubinstein is regarded as the ultimate source for key information.

For this seventh edition, the book returns to a single, clearly organised volume, and basic sciences are once again fully integrated within sections devoted to individual tumour entities. Entirely revised and updated throughout by a wide range of internationally revered authorities, the content reflects the latest tumour classification and grading while neuroradiologic correlation via state of the art neuroimaging techniques continues to be emphasised in all diagnostic entities. The offering is completed by a companion CD-ROM, providing quick and easy access to all the images from the book, retrievable by figure number, chapter title and keyword searches.


Content restructured and re-organised into a single volume for improved accessibility

Basic science fully integrated
Top quality colour photographs throughout, all presented on the fully searchable companion CD
Reflects the latest tumour classification and grading

Many new contributors including key international authorities
CONTENTS: Classification of tumors of the nervous system
Epidemiology of brain tumors: incidence, survivial and risk factors
Nervous system tumors and atomic bomb experience of Hiroshima and Nagasaki
Diffuse astrocytoma
Anaplastic astrocytoma
Astrocytoma of brain Stem
Astrocytomas of the spinal cord
Glioblastoma multiforme
Pilocytic astrocytoma and pilomyxoid astrocytomas
Pleomorphic xanthoastrocytomas
Astroblastoma
Oligodendrogliomas
Anaplastic oligodendrogliomas and mixed gliomas
Ependymomas, subependymomas, myxopapillary ependymomas
Monomorphous angiocentric glioma/angiocentric neuroepithelial tumor
Chordoid glioma of III ventricle
Choroid plexus tumors
Medulloblastoma
Cerebellar liponeurocytoma
Atypical teratoid/rhabdoid tumors
Melanotic neuroectodermal tumor of infancy
Olfactory neuroblastoma
Medulloepitheliomas
SPNET - neuroblastomas, ganglioneuroblastoma, malignant neuroblastic-glial tumors and ependymoblastomas
Ganglion Cell Tumors: gangliocytoma, ganglioglioma and anaplastic ganglioglioma
Desmoplastic infantile astrocytoma/desmoplastic infantile ganglioglioma
Extraventricular neurocytomas and unconventional glioneuronal tumors
Central neurocytoma
Dysembryoplastic neuroepithelial tumor
Dysplastic gangliocytoma of the cerebellum (Lhermitte - Duclos disease)
Hypothalamic neuronal hamartoma
Paragangliomas of the spine and skull base
Tumours of pineal parenchymal and glial cells
Meningiomas
Solitary fibrous tumors
Primary meningeal sarcoma
Hemangiopericytoma
Capillary haemangioblastoma
Cerebral sarcomas
Rhabdo- and leiomyosarcoma
Angiosarcomas and Kaposi's sarcoma
Hemangioendotheliomas
Meningeal melanocytoma, neurocutaneous melanosis and primary meningeal melanoma
Germ cell tumors
Totipotential cells of the distal spinal cord
Dermoid cyst, epidermoid cyst, and dermal sinus
Intracranial cysts of endodermal or respiratory epithelial origin
Lipomas and rare lipomatous tumours
Arachnoid cysts
Neuroepithelial cysts of the IV ventricle and extraventricular ependymal cysts
Ectopias and hamartomas
Tumours of the retina
Gliomas of the optic nerve and chiasm
Neoplasms of the sellar region
Chordoma and related lesions, chondrosarcoma and osteosarcoma of the calvarium
Primary tumors of cranial, spinal and peripheral nerves
Nervous system involvement by lymphoma, leukemia and other hematopoietic Cell Proliferations
Neurofibramotisis Type 1
Neurofibramotisis Type 2
Von Hippel-Lindau Disease
Li - Fraumeni syndrome and the p53 tumor suppressor pathway
Neuropathologic features of tuberous sclerosis
PTEN hamartomatous tumor syndromes
Nevoid basal cell carcinoma (Gorlin) syndrome
Hereditary colorectal cancer and brain tumor syndromes
Metastases
Appendix 1: Invasion and metastasis
Appendix 2: Molecular biology and genetic models of gliomas and medulloblastomas