In this newly updated, second edition of Molecular Diagnostics, notable practitioners describe how laboratory medicine is practiced today and illuminate how it will function tomorrow as the revolutionary advances afforded by molecular diagnostics become increasingly central to effective analysis. Proceeding from a discussion of elementary nucleic acid technology to a review of the more advanced techniques, the distinguished contributors lay the groundwork for a comprehensive understanding of their applications throughout clinical medicine. This new edition contains new chapters on bioinformatics. microarrays, methylation assays, FISH. laser capture microdissection, quality assurance, chimerism studies for bone marrow transplantation, and separate chapters on genetic counseling and ELSI (ethical, legal, and social issues).These new chapters represent developments in the past decade that have fundamentally changed the scope from molecular pathology to molecular diagnosis, highlighting the changing role of the clinical laboratorians who direct these efforts.