Edition after edition, Williams Hematology has guided generations of clinicians, biomedical researchers, and trainees in many disciplines through the origins, pathophysiological mechanisms, and management of benign and malignant disorders of blood cells and coagulation proteins. The book begins with the evaluation of the patient and progresses to the molecular and cellular underpinnings of normal and pathological hematology. Subsequent sections present disorders of the erythrocyte, granulocytes and monocytes, lymphocytes and plasma cells, malignant myeloid and lymphoid diseases, hemostasis and thrombosis, and transfusion medicine.



Featuring a brand-new full-color presentation, the Eighth Edition of Williams Hematology is extensively revised to reflect the latest views of experts in the field. Two new chapters examine the importance of genomics in hematology and cell therapy for tissue replacement, whereas other chapters have been revised to incorporate the newest clinical approaches to the leukemias and lymphomas, and the application of targeted therapy in the treatment of hematologic disorders.



New to this Edition:

* Full-color presentation conveniently integrates images of blood and tissue findings where they are cited in the text
* Two additional chapters, ?Epigenetics and Genomics,? and ?Principles of Multipotential Cell Therapy for Tissue Replacement,? offer insights into the application of genomic and monoclonal therapies to hematology and emphasize their role in improving diagnostic and therapeutic methods
* Expanded coverage of non-Hodgkin lymphoma includes separate chapters on its constituent diseases, providing an in-depth assessment of the diagnosis and management of these disorders
* A comprehensive discussion of erythrocytosis and thrombocytosis reviews reactive and malignant forms of myeloproliferation, encompassing new genetic advances in these disorders along with more targeted therapeutic approaches
* Companion CD includes a large selection of morphologies, illustrations, and drawings from the book, in a presentation-ready PowerPoint format

Authors: Kenneth Kaushansky, MD
Helen M. Ranney Professor and Chair
Department of Medicine
University of California, San Diego
La Jolla, CA
Marshall A. Lichtman, MD
Departments of Medicine and of Biochemistry and Biophysics
University of Rochester Medical School
Rochester, NY
Ernest Beutler, MD
(1928-2008)
Professor and Chairman
Department of Molecular and Experimental Medicine
The Scripps Research Institute
La Jolla, CA
Senior Consultant
Division of Hematology Oncology
Scripps Clinical Medical Group, Inc.
Clinical Professor of Medicine
University of California, San Diego
La Jolla, CA
Thomas J. Kipps, MD, PhD
Evelyn and Edwin Tasch Chair in Cancer Research
Professor of Medicine
Division of Hematology/Oncology
Deputy Director for Research Operations
Moores UCSD Cancer Center
University of California, San Diego
La Jolla, CA
Uri Seligsohn, MD
Professor and Director
Amalia Biron Research Institute of Thrombosis and Hemostatis
Department of Hematology
Chaim Sheba Medical Center
Tel-Hashomer and Sackler Faculty of Medicine
Tel Aviv University
Tel Aviv, Israel
Josef T. Prchal, MD
Professor of Medicine, Pathology, and Genetics
Hematology Division
University of Utah
Salt Lake City, UT
Department of Pathophysiology
First Faculty of Medicine
Charles University in Prague
Czech Republic