This one-of-a-kind reference provides a practical look at neurological disease and how it affects, and is affected by, other disease. It helps neurologists manage patients with co-existing medical conditions, and helps internists understand and treat the neurological manifestations of patients' primary diseases. A new emphasis on diagnosis and management - including advances in pharmacology, genetic-based therapies, and new imaging techniques - makes this 4th Edition more clinically valuable than ever!