Now in its Fourth Edition, this comprehensive, practical, and thoroughly illustrated reference offers valuable guidance in the diagnostic interpretation of lymph node biopsies. It provides encyclopedic coverage of all the various nonmalignant lesions, lymphomas, other neoplasms, and metastatic tumors in lymph nodes. The discussion of each pathologic entity includes definition, clinical syndrome, histopathology, and differential diagnosis.

This edition has more than 700 illustrations, including over 600 in full color. Dr. Ioachim is joined by a new co-editor, L. Jeffrey Medeiros, MD, from the University of Texas MD Anderson Cancer Center. All chapters have been extensively revised and a new chapter on genetics has been added.

A companion Website will offer the fully searchable online text and an image bank.

CONTENTS:

PART ONE THE NORMAL LYMPH NODE

Chapter 1 The Normal Lymph Node

PART TWO DIAGNOSTIC METHODS

Chapter 2 The Lymph Node Biopsy
Chapter 3 Cytopathology
Chapter 4 Electron Microscopy

PART THREE LYMPHADENITIDES

SECTION I VIRAL LYMPHADENITIDES

Chapter 9 Infectious Mononucleosis Lymphadenitis
Chapter 10 Cytomegalovirus Lymphadenitis
Chapter 11 Herpes Simplex Virus Lymphadenitis

SECTION II BACTERIAL LYMPHADENITIDES

Chapter 16 Ordinary Bacterial Lymphadenitis
Chapter 17 Cat-Scratch Lymphadenitis
Chapter 18 Bacillary Angiomatosis of Lymph Nodes

SECTION III MYCOBACTERIAL LYMPHADENITIDES

Chapter 22 Mycobacterium tuberculosis Lymphadenitis
Chapter 23 Nontuberculous Mycobacterial Lymphadenitis
A. Atypical Mycobacterial Lymphadenitides
B. Mycobacterium avium-intracellulare Lymphadenitis

SECTION IV FUNGAL LYMPHADENITIDES

Chapter 25 Cryptococcus Lymphadenitis
Chapter 26 Histoplasma Lymphadenitis
Chapter 27 Coccidioidomycosis Lymphadenitis

SECTION V PROTOZOAL LYMPHADENITIDES

Chapter 29 Toxoplasma Lymphadenitis
Chapter 30 Leishmania Lymphadenitis
Chapter 31 Filaria Lymphadenitis

PART FOUR LYMPHADENOPATHIES

SECTION I REACTIVE LYMPHADENOPATHIES

Chapter 32 Reactive Lymphoid Hyperplasia
Chapter 33 Atypical Lymphoid Hyperplasia
Chapter 34 Progressive Transformation of Germinal Centers

SECTION II LYMPHADENOPATHIES ASSOCIATED WITH CLINICAL SYNDROMES

Chapter 35 Kimura Lymphadenopathy
Chapter 36 Sinus Histiocytosis with Massive Lymphadenopathy
Chapter 37 Kikuchi Lymphadenopathy

SECTION III IATROGENIC LYMPHADENOPATHIES

Chapter 45 Drug-Induced Lymphadenopathy: Methotrexate
Chapter 46 Drug-Induced Lymphadenopathy

SECTION IV VASCULAR LYMPHADENOPATHIES

Chapter 47 Lymph Node Infarction
Chapter 48 Vascular Transformation of Sinuses

SECTION V FOREIGN BODY LYMPHADENOPATHIES

Chapter 49 Proteinaceous Lymphadenopathy
Chapter 50 Lipid Lymphadenopathy

SECTION VI LYMPH NODE INCLUSIONS

Chapter 54 Epithelial Cell Inclusions in Lymph Nodes
Chapter 55 Nevus Cell Inclusions in Lymph Nodes

PART FIVE LYMPHOMAS

SECTION I NOMENCLATURE AND CLASSIFICATION OF LYMPHOMAS

Chapter 56 Nomenclature and Classfication of Lymphomas

SECTION II HODGKIN LYMPHOMA

Chapter 57 Hodgkin Lymphoma: Classical
Chapter 58 Hodgkin Lymphoma: Nodular Lymphocyte Predominant

SECTION III PRECURSOR B-CELL AND T-CELL NEOPLASMS

Chapter 59 Lymphoblastic Leukemia/Lymphoma

SECTION IV MATURE B-CELL NEOPLASMS

Chapter 60 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Chapter 61 Lymphoplasmacytic Lymphoma
Chapter 62 Hairy Cell Leukemia

SECTION V MATURE T-CELL NEOPLASMS

Chapter 71 Adult T-Cell Leukemia/Lymphoma
Chapter 72 Mycosis Fungoides

PART SIX GRANULOCYTIC, HISTIOCY TIC, AND DENDRITIC CELL NEOPLASMS

Chapter 76 Myeloid Sarcoma
Chapter 77 Histiocytic Sarcoma

PART SEVEN LYMPHOPROLIFERATIVE DISORDERS ASSOCIATED WITH IMMUNE DEFICIENCY

Chapter 79 Lymphoproliferative Disorders Associated with Congenital Immune Deficiencies
Chapter 80 Post-Transplant Lymphoproliferative Disorders

PART EIGHT SPINDLE CELL NEOPLASMS OF LYMPHNODES

Chapter 82 Palisaded Myofibroblastoma
Chapter 83 Inflammatory Pseudotumor of Lymph Nodes

PART NINE VASCULAR NEOPLASMS OF LYMPHNODES

Chapter 84 Hemangiomas/Hemangioendotheliomas

PART TEN META STATIC TUMORS IN LYMPHNODES

Chapter 86 Tumor Metastases in Lymph Nodes

INDEX