This new reference examines specimen processing of effusion fluids, detailing the steps needed to obtain more accurate diagnoses while avoiding common pitfalls. A methodical, algorithmic approach to the evaluation and interpretation of specimens enables you to establish a definitive diagnosis in these often difficult cases. User-friendly features - combined with extensive tables and algorithms - facilitate ease of interpretation, and highlighted information makes the most essential concepts easy to reference quickly. CONTENTS: 1. Introduction 2. The panorama of different faces of mesothelial cells 3. Approach to diagnostic cytopathology of serous effusions 4. Diagnostic pitfalls in effusion fluid cytology 5. Immunocytochemistry of effusion fluids: introduction to SCIP approach 6. Reactive conditions 7. Diagnostic cytopathology of peritoneal washing 8. Mesothelioma 9. Metastatic carcinoma in effusions 10. Metastaic sarcomas, melanoma, and other non-epithelial malignancies 11. Where do they come from? Evaluation of unknown primary site of origin 12. Hematolyphoid disorders 13. Flow cytometry, molecular techniques, and other special techniques Appendix 1: Collection and processing of serous cavity fluids for cytopathologic evaluation Appendix 2: Immunocytochemistry of effusions - processing and commonly used immunomarkers Index
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