Since publication of the First Edition many advances have been made and the Second Edition incorporates these changes in focus and on techniques. There is an additional chapter on respiratory and cardiac disease, and given the continued focus of companion animal practitioners on vaccine-related issues, a new chapter is devoted entirely to the subject of vaccinology. The Second Edition includes approximately 200 new photographic images, an updated list of further reading and an extensive glossary of terms.

Contents: Glossary. 1. Basic Immunology, 2. Immunopathological Mechanisms, 3. The Basis of Immune-Mediated Disease, 4. Immune-Mediated Haematological Disease (with A. J. Mackin), 5. Immune-Mediated Skin Disease (with S. E. Shaw), 6. Immune-Mediated Musculoskeletal and Neurological Disease (with D. Bennett), 7. Immune-Mediated Alimentary Disease (with E. J. Hall), 8. Immune-Mediated Respiratory and Cardiac Disease, 9. Immune-Mediated Endocrine Disease (with S. E. Shaw), 10. Immune-Mediated Renal and Reproductive Disease (with A. J. Mackin), 11. Immune-Mediated Ocular Disease (S. M. Crispin), 12. Immunodeficiency Disease, 13. Immune System Neoplasia (with J. M. Dobson), 14. Multisystem and Intercurrent Immune-Mediated Disease, 15. Disease, of the Lymphoid Tissue, 16. Immunotherapy, 17. Vaccination. Further reading. Index.